Programme de recherche portant sur les mécanismes cellulaires et génétiques définissant la prédisposition au diabète de type 1

 

Sylvie Lesage

Université de Montréal

 

Domaine : maladies infectieuses et immunitaires

Programme chercheurs-boursiers - Senior

Concours 2015-2016

Our research goals are aimed at defining homeostatic regulation of cell populations composing the immune system and to identify their impact on the susceptibility of complex genetic diseases such as autoimmune diseases.

In particular, we study variations of T cell and dendritic cell sub-populations in various strains of mice. The ultimate goal is to increase our understanding of the cellular population dynamics in the immune system. This research will provide the basis for cellular therapy protocols aimed at restoring the immune balance to prevent the onset or abrogate the progression of various auto-immune diseases, namely type 1 diabetes.