Barbara Papadopoulou, a full professor in the Microbiology, Infectology and Immunology department of Université Laval's faculty of medicine, is also a researcher at the CHU de Québec Research Center-Université Laval.
Ms. Papadopoulou obtained a doctorate in pharmacology from the University of Athens in 1981, a Master's degree from the Université de Paris XI in 1983 and a doctorate in microbiology and molecular biology from the Pasteur Institute in 1988. She went on to postdoctoral studies in yeast genetics (Saccharomyces cerevisiae) at the University of Amsterdam (1988-1990), and then in molecular parasitology at CHUQ (1991-1993).
A Burroughs Wellcome Fund awardee in molecular parasitology, Ms Papadopoulou is a member of a CIHR (Canadian Institutes of Health Research) group and of a FRQNT (Fonds de recherche du Québec – Nature et technologies) strategic cluster of researchers, both groups of which are involved in the area of host-pathogen interactions. Her research with CHU de Québec Research Center-Université Laval deals primarily with pathogenesis of the parasitic protozoan Leishmania. Her research group uses a combination of genomic and proteomic approaches with a view to achieving two goals: to identify the genes specifically expressed at the intracellular stage (macrophages in the vertebrate host) of Leishmania, and to study their stage-specific regulation mechanisms and their potential function in the intracellular survival of the parasite and in disease development. Her group is also interested in the intracellular signalling mechanisms that regulate mRNA translation under various environmental stresses. The aims of the research include the development of novel vaccine strategies against selected intracellular pathogens such as Leishmania.