The Fonds de recherche du Québec – Santé (FRQS) is administered by a board of directors consisting of an odd number of no more than 15 members, including the Chief Scientist Officer and the Scientific Director. The Board of Directors is supported by four standing committees, namely an ethics and scientific integrity committee, a governance committee, a program committee and an audit committee.

The joint committee on the responsible conduct of research reports to the boards of directors of the three Fonds de recherche. The intersectoral student committee reports directly to the Chief Scientist Officer.