Étude des dimensions psychosociales de l'adhésion au traitement médicamenteux


Sophie Lauzier



Domaine : santé des populations

Concours 2013-2014


Institut national d'excellence en santé et en services sociaux

Adherence to treatment, namely, the patient's complying with the treatment recommendations agreed upon with the prescriber, is an important determinant of optimal drug use. Results of numerous studies indicate that adherence to drug therapy is suboptimal for a substantial proportion of individuals with chronic diseases. Many researchers and organizations consider development of interventions to promote adherence a priority. However, development of these interventions is limited by our partial understanding of the psychosocial factors that may influence adherence. Indeed, there are modifiable factors associated with the adoption of many health behaviors and these should be targeted in our interventions.

The objectives of my research program are: 1) to identify psychosocial factors influencing adherence to medication, and 2) to develop interventions that promote adherence. Two main studies in this program constitute the cornerstones of the development of interventions. The first is a multi-center study designed to identify the psychosocial determinants of adherence to adjuvant hormonal therapy for breast cancer during the 12 months following the first prescription. The second aims to develop a pharmacist-based intervention to improve adherence to antidepressant medication. The ultimate goal of this work is to optimize the use of widely and readily available therapies whose demonstrable benefits can improve the health of individuals affected by these chronic diseases.