Troubles du sommeil chez les enfants: les effets du traitement sur les résultats de santé

Chercheurs-boursiers cliniciens -Junior 2 | Concours 2012-2013

Evelyn Constantin

Institut de recherche du Centre universitaire de santé McGill (CUSM)


Domaine : Santé de la mère, des enfants et des adolescents 

Sleep disorders affect 6 million Canadians, costing the health care system $1-2 billion yearly. Children with obstructive sleep apnea (OSA), a common sleep disorder, have significant health care use. In younger children, OSA is usually caused by blockage of the airway by large tonsils and adenoids; treatment is the surgical removal of tonsils and adenoids (adenotonsillectomy, T&A). In older children, obesity is a major factor and treatment is often overnight positive airway pressure (PAP). If OSA is not treated, significant problems can occur affecting the heart, blood sugar levels, behaviour, and learning. OSA is strongly linked to other serious conditions like asthma and obesity. It is unknown how OSA treatments affect health and health care use. Another area of concern is the treatment of sleep disorders in children with cerebral palsy (CP). Children with CP are at high risk of disordered sleep and poor health outcomes. In the past few years, I have studied the benefits of T&A on health outcomes. My ongoing research program is focused on three studies: Project 1 (currently underway across Canada): I will determine if, in obese children with OSA, increasing number of hours of PAP therapy for one year, improves sugar control and other health outcomes. Project 2: I will use healthcare data to determine how T&A affects health care use and health practices in Quebec. Project 3: I will perform a pilot randomized clinical trial to evaluate melatonin treatment on sleep in children with CP. My research program is novel because it will 1) lead to new knowledge on how OSA treatment affects children¿s health and the health care system; 2) understand the practice of T&A in Quebec; 3) evaluate, for the first time, treatment for sleep disorders in children with CP.