Prévenir les infections: à l'hôpital et dans la communauté

 

Caroline Quach-Thanh

Centre hospitalier universitaire Sainte Justine

 

Domaine : maladies infectieuses et immunitaires

Programme Chercheurs-boursiers de mérite

Concours 2018-2019

With the emergence of new infections and of antibiotic resistant microorganisms, preventing infections is often the most effective - and least expensive - solution. In Canada, adverse healthcare-related outcomes including healthcare-associated infections, are estimated to cause an economic burden of close to $ 110 billion annually. Between 8 and 12% of hospitalized patients will suffer such infection, with an increasing proportion caused by resistant organisms and against which we have fewer and fewer therapeutic options.

Since the beginning of my research career, my goal has been to reduce and even defeat healthcare-associated infections. Building on the gains made in my first 12 years of FRQ-S funding, the objective of my program for the next four years will be to understand what "works". To do this, I succeeded in building a network of collaborators from multiple disciplines: industrial and civil engineers, medical anthropologist, biochemist and chemist, both in Quebec and internationally. Through this network and future projects, we will establish a common database to selected teaching hospitals in Montreal and Brussels to first identify priorities for infection prevention and control and establish improvement processes. We will then determine which measures reduce the risk of infection transmission in healthcare settings. We also want to validate the capacity of a new low-cost, high-performance method that we hope will enable us to quickly identify microorganisms that are part of an outbreak.

This rapid method can be carried out in hospitals, thus reducing the need for costly and laborious techniques in reference laboratories. Finally, we will evaluate the impact of changes in the hospital environment on the risk of infections.