Ostéoporose et fractures : améliorer les résultats cliniques

 

Suzanne Morin

Université McGill

 

Domaine : appareil locomoteur et arthrite

Programme chercheurs-boursiers cliniciens - Junior 2

Concours 2015-2016

Osteoporosis is a chronic disease characterized by microarchitectural deterioration of bone leading to skeletal fragility and fractures, which are associated with excess mortality, pain and decreased autonomy. Personal and societal costs of fractures are high, making it imperative to develop collaborative strategies that aim to accurately identify the population at risk, and improve clinical outcomes.

I intend to evaluate the complications that arise following hip, pelvic and thigh fractures, in order to enhance quality of care during the hospital stay and following discharge and to develop preventive strategies to reduce negative outcomes.

Fractures cause pain, which if relieved rapidly, improves wellbeing and reduces negative outcomes. I investigate novel ways to implement best-care practices in pain management in acute care facilities such as the emergency department, to ensure that analgesia is administered rapidly and effectively to patients with fractures.

Researchers have recently questioned the safety of calcium supplements as they might increase the risk of cardiovascular events, such as heart attacks and strokes. Because there are methodological concerns with these studies and because the exact cause behind these negative effects is not yet determined, many questions remain. Could calcium supplements be good for your bones but bad for your heart? We propose to estimate the effect of dietary intake of calcium as compared to supplemental calcium on markers of vascular and bone health in postmenopausal women in a clinical trial to determine whether calcium supplements have a different effect on vascular health than calcium obtained from the diet and shed light on the mechanisms that underlie these effects.

Achieving dissemination and uptake of health research depends on effective partnerships between researchers, clinicians, decision-makers and patient-partners; this purpose supports my research program.