Optimisation des périodes de transition en insuffisance rénale terminale; équilibre entre les besoins d'une population vulnérable et les mesures d'incitation à la dialyse à domicile


Annie-Claire Nadeau-Fredette

CIUSSS de l'Est-de-l'Île-de-Montréal


Domaine : santé des populations

Programme Chercheurs-boursiers cliniciens - Junior 1

Concours 2018-2019

Partenaire :

Fondation canadienne du rein

Severe chronic kidney disease is affecting a large number of patients for whom dialysis treatments are often required. Home dialysis therapies (peritoneal dialysis and home hemodialysis) are increasingly promoted for patients undergoing dialysis as they are associated with benefits including a better quality of life and fewer complications.

Overall, patients living with chronic kidney disease go through many transition periods as they progress from kidney disease to different dialysis therapies. These transition phases present an increased risk of adverse events such as medical complications, hospitalization, lower quality of life and death. Patients undergoing home dialysis treatment are at higher risk of modality change and they represent a targeted group in whom to evaluated transition periods.

The objective of this research program is to evaluate the characteristics, risk factors and outcomes associated with transition periods in patients with severe kidney disease. The first project will evaluate the risk of death and hospitalization in patients before start of home dialysis and after transfer to another dialysis therapy. The second project will see how quality of life change during the progression from severe chronic kidney disease to dialysis therapies. Finally the third project will identify the barriers and facilitators perceived by patients, their family members and nephrologists to the adoption of peritoneal dialysis and home hemodialysis therapy.

Globally, this project aims to identify strategies that will improve cares provided to patients living with advanced chronic kidney disease and undergoing dialysis treatments.