Optimisation de la ventilation assistée chez l'enfant


Guillaume Emeriaud

Centre de recherche du Centre hospitalier universitaire Sainte-Justine


Domaine : santé circulatoire et respiratoire

Programme chercheurs-boursiers cliniciens - Junior 2

Concours 2015-2016

The most severely ill children are hospitalized in pediatric intensive care units. Most of these children are unable to assume their breathing, and they require a mechanical ventilation. The mechanical ventilation, which is delivered by a respirator, is a life support treatment, but we have previously shown that the mechanical ventilation needs to be improved in children because respirators are not able to adapt their support to the child's needs. We have shown that a new ventilation mode (NAVA) allows the respirator to adapt more precisely to the breathing of children.

This research program aims to improve both the effectiveness and safety of mechanical ventilation, in order to promote faster recovering of children in intensive care. Some studies will aim to improve the adaptation of ventilation to the specific needs of each child. These studies will be based in particular on the development of automatic systems which will permit the physicians to always know if the ventilation used is the most appropriate for the child's condition. This will allow faster responses when adjustments are needed, reducing the risk of complications. Other studies will test if the NAVA mode can facilitate the recovery of children in different conditions (especially after cardiac surgery, or when a lung disease prevents proper oxygenation).

By improving the efficiency, the safety, and the appropriate adaptation of ventilation to each child's needs, we expect that this program will lead to shorter stay of children in pediatric intensive care unit, and thus will improve the comfort of these patients while reducing health care costs.