Évaluation des nouvelles techniques et technologies pour le traitement des pathologies articulaires dégénératives du membre inférieur


Pascal-André Vendittoli

Centre de recherche de l'Hôpital Maisonneuve-Rosemont


Domaine :  appareil locomoteur et arthrite

Programme chercheurs-boursiers-cliniciens - Senior

Concours 2017-2018

Musculoskeletal diseases are the most common cause of chronic pain and disability. Joint degeneration (osteoarthritis) is the most common musculoskeletal pathology and affects more than 1 on 8 Canadian; the hip and the knee are the most affected joints. Considering the limited medical treatment, a large proportion of subjects with osteoarthritis of the knee or hip will be treated by a surgical joint replacement procedure.

Despite the high success of this procedure and the very positive cost-benefit ratio, five issues persist: 1 - deficient identification of individual success and failure factors in the candidates selection; 2 - the occurrence of avoidable complications (control of pain, medical and orthopaedic complications); 3 - the implantation of prostheses that do not allow a natural joint function; 4 - the use of non-optimal surgical techniques (missing precision or not respecting the patient's anatomy) and 5 - the introduction of implants with manufacturing defects or not providing good results.

Dr. Vendittoli's research program aims to optimize the management and treatment of patients with hip or knee joint degeneration. The program include clinical studies assessing the effectiveness and innocuous of news prosthesis or surgical techniques. The other goals of this program include the identification of success factor in arthroplasty permitting better subjects identification; development of new surgical techniques and creation of new implants which provide optimal clinical functions. The program contains only original and independent industry projects; their funding is mainly through donations from patients or industry to the Maisonneuve-Rosemont Hospital Foundation.