Efficacité et sécurité des analgésiques et sédatifs aux soins intensifs


Yoanna Skrobik

Centre universitaire de santé McGill


Domaine : santé circulatoire et respiratoire

Programme chercheurs-boursiers cliniciens - Junior 2

Concours 2015-2016

Pain control and adjustment of medications for anxiety are a priority for Intensive Care Unit (ICU) patients. Part of this program aims to improve both assessments and medication administration to tailor it to individual patient needs.

Most ICU patients, particularly those on mechanical ventilation, routinely receive intravenous sedatives and analgesics. In addition to being useful, these medications can cause side effects such as decreases in the level of consciousness, leading to drug-induced coma. This coma may be due to the administration of drugs, to their metabolism, or to drug interactions in the intensive care setting. Two studies aim to identify what mechanisms are associated with having been made comatose in the intensive care unit.

The overall theme is one of improving the effectiveness and safety of pharmacological pain and sedation management.