Développement et validation de techniques d'imagerie pour l'investigation des pathologies musculosquelettiques

 

Nathalie Bureau

Université de Montréal

 

Domaine : appareil locomoteur et arthrite

Programme Chercheurs-boursiers cliniciens - Junior 2

Concours 2019-2020

Partenaire:

Fondation de l'Association des radiologistes du Québec

Musculoskeletal diseases are the leading cause of chronic pain in the adult population. Osteoarthritis of the knee is a debilitating disease and is endemic in developed countries. With the ageing of the population and the high prevalence of obesity, The Arthritis Alliance of Canada predicts that by 2040, 1 in 4 Canadians will suffer from osteoarthritis. Shoulder and elbow tendon injuries also represent a large proportion of musculoskeletal diseases and are the most common causes of injury leading to work compensation and absenteeism. There is no consensus on the optimal treatment regimen for musculoskeletal diseases in the medical community and patients are often confronted with the absence of effective care management. There is an urgent need to define diagnostic strategies and therapeutic algorithms to improve the care management of musculoskeletal diseases.

The goal of this research program is to develop and validate new imaging techniques to improve the diagnosis, monitoring and treatment of musculoskeletal diseases. In the first project, we will evaluate the efficacy of a novel ultrasound-guided percutaneous intervention to treat lateral epicondylitis of the elbow, commonly known as ‘tennis elbow'. In addition, we will assess quantitative ultrasound techniques for monitoring the tendon healing response. In the second project, we will assess artificial intelligence techniques to improve the diagnosis and help predict the evolution of osteoarthritis of the knee. In the third project, we will develop and optimize a technique of magnetic resonance imaging to evaluate the loss of muscle elasticity in patients with rotator cuff tendon tears of the shoulder. Ultimately, this research program aims at developing imaging strategies to improve the clinical care of patients with musculoskeletal diseases.