Dérèglement épigénétique dans le cancer du sein

 

Michael Witcher

Institut Lady Davis de recherches médicales de l'Hôpital général juif

 

Domaine :   cancer

Programme chercheurs-boursiers - Junior 2

Concours 2017-2018

Breast and Ovarian cancers are diverse and complex diseases. But, through uncovering the cellular defects that give rise to these cancers, we predict that we can find new means to more effectively treat these patients. The projects funded in my lab are discovering that defects in the regulation of tumor DNA are present in many tumors, and these defects predict great sensitivity to drugs targeting our genomes. We are testing these drugs using diverse models that will hopefully guide the clinical use of these anti-cancer therapeutics.