Comprendre et utiliser les trajectoires pour mieux personnaliser les traitements en douleur : un programme de recherche


Gabrielle Pagé

Centre hospitalier de l'Université de Montréal [CHUM]


Domaine : neurosciences, santé mentale et toxicomanies

Programme Chercheurs-boursiers - Junior 1

Concours 2019-2020

One in five Canadian suffers from chronic pain and this is associated with negative physical, emotional and social consequences. Many patients consult with multiple health care providers to obtain pain relief. Opioids are often used to manage chronic pain; however scientific data available to date does not provide strong support for their long-term effectiveness. In this context, it is essential to better identify patient profiles most and least likely to develop chronic pain and to respond to therapeutic approaches.

This objective will be examined through two research themes. First, two studies will examine the transition from acute to chronic pain and the persistence of opioid use (theme 1). The first study will examine how pain characteristics interact with psychological factors to predict the development of chronic low back pain. The second study will aim to understand the different patterns of opioid use after bariatric surgery and identify predictors of these profiles. Last, using medico-administrative databases and patient registry, the second theme will examine chronic pain and health care utilization trajectories. The third project will specifically look at trends in opioid use among chronic pain patients attending multidisciplinary pain clinics. The last project will identify different profiles of health care utilization from primary to tertiary care among chronic pain patients.

By using novel methodological approaches, this research program will make it possible to identify different profiles of patients that share similar trends in pain evolution and health care use. Identifying factors associated with these different profiles and trajectories will guide the development of tailored prevention and intervention strategies to optimize chronic pain treatments.