Compréhension de la pathogénèse de maladies neurodégénératives et développement de stratégies thérapeutiques

 

Francesca Cicchetti

Centre de recherche du CHUL

 

Domaine : Neuroscience, santé mentale et toxicomanies

Programme chercheurs nationaux

Concours 2014-2015

Our research program is built on 3 distinct research themes: 1) to better understand the phenomenon that may contribute to the development or the propagation of pathological aspects found in neurodegenerative and mental disorders; 2) develop therapeutic strategies that would allow an early or late intervention in the evolution of the disease; 3) study the mechanisms of action underlying the beneficial and/or detrimental effects of current experimental therapies (cell transplantation and deep brain stimulation) in order to improve these methodologies for the clinic.

Our research program is based on translational research, from the animal model to the clinic, with the goal to develop novel therapeutic targets for individuals suffering from Parkinson¿s disease, Huntington¿s disease and Schizophrenia.