One of the greatest healthcare challenges is the increasing costs and social burden of chronic disease - a challenge that the healthcare system is poorly equipped to address. Self-management refers to learning and practicing skills necessary to carry on an active and emotionally satisfying life in the face of a chronic condition. This requires providing patients with effective tools and strategies to manage their health and to develop the confidence needed to uptake healthy behaviors and stop unhealthy ones. Self-management support for patients by the care team is recognized as an integral element needed for improving health outcomes by guiding individuals to care for their own health and to make positive health choices. Providing this type of support requires an interdisciplinary team approach to patient care and may be facilitated by the use of technology to extend care outside of the clinic setting. While advances have been made over recent years, significant gaps remain in understanding how best to prevent and improve the health of individuals with chronic disease. The first aim of this research program is to develop and identify the best approaches for evaluating changes in peoples¿ health. The second aim is to evaluate the benefits of web-based self-management tools. Finally, the third aim will be to evaluate existing chronic disease management programs to identify what is working and where changes may be needed to improve patient care. The overreaching goal of this research program is to optimise care and ultimately improve quality of life of persons with chronic disease.