Étudiant-chercheur étoile January 2014


Benoît Cossette, étudiant-chercheur étoile, FRQS

Benoît Cossette

PhD student in Pharmacology
Université de Montréal


Award-winning publication: Impact of maternal use of asthma-controller therapy on perinatal outcomes

Published in: Thorax, 68(8), 724-730, 2013.
 

Abstract

"The use of asthma medication by women during pregnancy has been shown to have a favourable safety profile: it does not lead to harmful effects, especially considering the risks of inadequately controlled asthma to the foetus. My study better quantifies the risks and benefits of asthma medications, such as long-acting bronchodilators, during pregnancy by demonstrating their favourable safety profiles with regards to preterm birth. Carried out on a higher number of pregnant women who controlled their asthma with medication than previous studies, my research showed that low to moderate doses of inhaled corticosteroids had a favourable safety profile. Still, certain doubts remain as to the use of high doses."

Benoît Cossette's work validates the use of certain asthma medications during pregnancy. In the longer term, the findings are expected to lead to further studies to assess the safety profiles of higher doses of inhaled corticosteroids. The data will help physicians who treat pregnant women suffering from asthma optimize their treatment choices to foster foetal development and maternal health.