Research on Age-related Macular Degeneration (ADM program)


Summary

Competition year :

2017-2018

 

Deadline (notice or letter of intent) :

August 31st, 2016, 4:30 PM

 

Deadline (application) :

December 1st, 2016, 4:30 PM

 

Amount :

Maximum of $50,000 per year

 

Duration :

Maximum of 2 years, non renewable

 

Announcement of results :

April 2017

 

Objectives

The objective of this funding program, in partnership with the Antoine-Turmel Foundation (ATF) and the FRQS Vision Health Research Network (VHRN), is to develop knowledge in the age-related macular degeneration (AMD) area to better treat, rehabilitate, and even cure patients with AMD. In order to reach these goals, this program favors the development of a critical mass of Québec researchers in AMD as well as the positioning of Québec as a global leader in this area by using strategic and structuring approaches.

By becoming a member of the VHRN, the awardees of this AMD program will have access to all resources developed by the network (common infrastructures, databases, tissue banks, etc.).

Program rules that prevail are those of the PDF version.
Program rules

 

 


1.

PROJECT ELIGIBILITY

Priority themes

This program is entirely dedicated to AMD research in all its forms (fundamental, clinical or translational research, epidemiology/public health, and rehabilitation). Any research methodology that would have the potential to help improving the knowledge on AMD is eligible.

Objectives

The main objectives of this program are to:

  • Develop better treatments for patients with AMD

  • Reduce significantly the disease course

  • Delay the start, or even prevent,  the disease

  • Develop rehabilitation's programs for patients with advanced illness to allow a better life with AMD

 


2.

APPLICANT ELIGIBILITY

Conditions

  • The project's team must include one Principal Investigator (PI) and co-investigators having the status of independent researcher as defined in Annex 1c of the Common General Rules, and working in a university or an institution in the health and social services network; a minimum of 2 co-investigators is required

  • Including young researchers among the co-investigators is strongly encouraged

  • The PI must demonstrate that he/she will devote a sufficient amount of research time to the project to ensure its success

  • Multidisciplinarity, intersectoriality and complementarity of skills of the research team will be considered as an asset

Postdoctoral trainees cannot apply to this program as PIs or
co-investigators.

Professional corporations

Clinical researchers must prove that they are members in good standing of the professional order governing them in Québec, have a valid license to practice in Québec and have professional liability insurance.

Multiple applications

Researchers may only submit one application to this program as a PI.

Researchers may submit several applications to this program as a co-investigator.

Affiliation, citizenship and residence

The principal investigator and the co-investigators must:

  • Be affiliated with a Québec university

  • Be Canadian citizens or permanent residents as defined in section 2.1 of the Common General Rules and domiciled in Québec

Collaborators may be from outside Québec. However, no funds will be transferred outside the province.

Ethics

PIs and co-investigators must comply with the ethical regulations as defined in sections 5.3 and 5.4 of the Common General Rules.

Basic training in research ethics

Basic training in research ethics is mandatory for all FRQS awardees when their research project involves human subjects.

The term "research project involving human subjects" applies when the research project involves:

  • Living human subjects

  • Cadavers, human remains, tissues, biological fluids, gametes, embryos or fetuses, cells or genetic materials

  • Personal information on file. Personal information is defined as information that enables a person to be identified

Awardees must successfully complete levels 1 and 3 of the Online Tutorial in Research Ethics set out by the Ministère de la Santé et des Services sociaux (MSSS).

PIs and co-investigators must complete the training before receiving the first payment of their grant.

 


3.

REQUIRED DOCUMENTS – LETTER OF INTENT

Transmission of the documents via the FRQS website only.

Any missing document or document that is not in conformity with the program rules and forms
may result in the ineligibility of the funding application.

Principal investigator

Only researchers whose letters of intent are selected will be invited to submit a full application (see the Evaluation section).

FRQS will send by email a confirmation of the acceptance or rejection of the letter of intent of each candidate.

Co-investigators

  • Canadian Common CV , Funding CV version for the FRQS (updated since June 2014)

  • Detailed contributions updated since June 2014 (attachment required through the FRQS Electronic Portfolio on the Canadian Common CV page) , consult the Guidelines for the CV attachment available in the toolbox

 


4.

REQUIRED DOCUMENTS – COMPLETE APPLICATION

Transmission of the documents via the FRQS website only.

Any missing document or document that is not in conformity with the program rules and forms
may result in the ineligibility of the funding application.

Principal investigator

  •  Canadian Common CV , Funding CV version for the FRQS (updated since June 2014)

  • Detailed contributions updated since June 2014 (attachment required through the FRQS Electronic Portfolio on the Canadian Common CV page) , consult the Guidelines for the CV attachment  available in the toolbox

  • Electronic form Complete application (Demande complète)
    PDF version - for information

  • Letter of support from the administrators of the institution or university department in which the research will be carried out (for the PI only)

  • Letter of support from a collaborator or a partner, if applicable

  • For a clinical PI: a letter from the director of the clinical department or the dean of the faculty specifying the number of hours for which the applicant will be released from his/her clinical obligations to carry out the research project

  • A copy of the Certificat de sélection du Québec, the permanent resident card, or the work visa if applicable

Co-investigators

  • Canadian Common CV , Funding CV version for the FRQS (updated since June 2014)

  • Detailed contributions updated since June 2014 (attachment required through the FRQS Electronic Portfolio on the Canadian Common CV page) , consult the Guidelines for the CV attachment available in the toolbox

  • For a clinical PI: a letter from the director of the clinical department or the dean of the faculty specifying the number of hours for which the applicant will be released from his/her clinical obligations to carry out the research project

  • A copy of the Certificat de sélection du Québec, the permanent resident card, or the work visa if applicable

 


5.

RESEARCH LOCATION

Choice of research location

An FRQS centre or group, an institution administered by the Ministère de la Santé et des Services sociaux (MSSS) or a Québec university.

Change of research location

The FRQS expects that the grantee will conduct his/her project at the same institution or university that initially endorsed the application throughout the entire grant period.

The grantees who wish to change their research location must submit by email an official request to the FRQS. The request must detail the reason(s) for the change and describe all possible consequences on the research project.

University or institutional authorities must notify the FRQS in writing once they have approved the change of location.

The acceptance of the new grantee in their new research centre or university department must also be done in writing to the FRQS by the director.

 


7.

AMOUNT OF THE GRANT

Amount

Up to $50,000 per year

Indirect research costs

The grants awarded under this program are eligible to receive an additional amount to cover indirect costs of research of the institutions. However, the FRQS is not responsible for the amounts paid by its partners. The details on indirect costs of research reimbursement will be available at the time of the grant.

 


8.

ELIGIBLE EXPENDITURES

Eligible

  • Salaries for research assistants

  • Remuneration of resource persons who are vital to the project

  • Remuneration of students (master and Ph.D.) and postdoctoral fellows in their first year only.  Students and postdoctoral fellows  must apply to provincial and national competitions for subsequent funding

  • Exceptionally, expenses to acquire equipment are eligible, conditional upon adequate justification in the proposal (maximum of $6,000/year)

  • Research material (including purchasing and housing for animals) and all other expenses required to carry out the research project, conditional upon adequate justification in the proposal

  • Equipment or platform user fees

  • Fees and reimbursements of travel expenses for research human subjects

  • Participation to conferences (up to 3% of the grant amount), from year 1

Non eligible

  • Remuneration of the PI, co-investigators, and collaborators

  • All indirect expenditures related to layout organization or reorganization, facilities leasing and maintenance or the indirect costs covered by the host institution

  • Funds must not be transferred outside of Québec

 


9.

EVALUATION

Letter of intent

The letter of intent is used to:

  • Determine the applicants' eligibility

  • Assess the relevance of the application

  • Establish a peer review committee with relevant expertise

Only applicants whose letter of intent has been considered eligible will be invited, by email from the FRQS, to submit a complete application.

Complete application

The applications will be evaluated by a peer review committee composed of experts from clinical and scientific institutions chosen by the FRQS according to the rules in effect for the constitution of review committees.

Representatives from the Antoine-Turmel Foundation and VHRN may sit on the evaluation committee as observers without the right to vote.

In addition to answering the specific objectives of the AMD program, the teams should pay particular attention to the strategic and structuring aspects of their research projects. These two aspects will be the guiding principles for the evaluation of the projects.

By structuring, it is meant that the projects will have to consolidate and accelerate the development of Québec AMD research by:

  1. mobilizing the available resources in the AMD community

  2. raising awareness and involving the different actors (researchers, clinicians, decision makers, non-profit organizations, partners, and patients) who can facilitate the AMD research and the implementation of the results

The recruiting and the development of a critical mass of scientists in AMD Québec research will also have a structuring impact.

The strategic aspect is related to the approach used by the researchers and the efforts and resources they will utilize to optimize their chances to reach the objectives of the program. New funding, public or private investments, and partnerships with the industry are examples of leverage effects resulting from a project. Visibility and impact at the international level, and consolidation of key collaborations are other examples.

 

The other evaluation criteria for the complete application will be:

Research project

  • Originality and coherence of the project

  • Clarity of the objectives

Research team

  • Scientific quality of the researchers

  • Complementarity of the researchers' expertises

  • Scientific achievements (publications, development of structuring initiatives, visibility in Canada and/or internationally, etc.)

  • Role in training young scientists

Networking/Partnerships

  • The research project described measures ensuring a mesh with members of the local research community, national and international decision-makers and / or practice settings

  • Financial or non-financial partnerships will be considered as an asset

Feasibility

  • Scientific and technical feasibility

  • Realism of the timeline and relevance of the monitoring indicators

Short term benefits

In the short term, how will this project allow meeting the objectives of the program?

  • Project impact in terms of acquisition of knowledge and skills

  • Project impact on the development of new concepts and models, instruments, approaches and methods, the final goal being to better treat or rehabilitate patients with AMD

Knowledge transfer

  • Proposed strategies to ensure that research results are used in the development and/or implementation of:

- better treatments

- better tools for rehabilitation or prevention

- better programs

- new practices or care policy for patients with AMD

Budget

  • Adequate budget justification in the proposal

 


10.

RESEARCH OUTCOMES AND KNOWLEDGE TRANSFER

Submission of reports and presentation

In accepting the grant, the grantees agree to submit scientific and financial reports by the deadlines determined by the FRQS. The results of all funded projects will have to be presented at the VHRN annual meeting.

Use and dissemination of the results by partners

The grantees authorize the partners to use final report and published research outputs (scientific publications, conferences, symposia, conventions or e-publication) for reproduction, translation, execution or public extension purposes through whatever means or for any other non-commercial purposes, provided there is no infringement of copyright law.

Knowledge mobilization

The FRQS encourages awardees to conduct and participate in knowledge mobilization activities (transfer, sharing, development, enhancement and dissemination) with practice settings and the general public, where such activities are relevant. Please read the document Knowledge Mobilization in the toolbox.

 


11.

APPLICANT'S AGREEMENT

 

By submitting an application, the applicant must: